PATH 205.3 Lecture Notes - Lecture 21: Oncotic Pressure, Hydrostatics, Capillary Pressure
Document Summary
Objectives: define, give clinical examples and know the clinical effects of, edema, hemorrhage, hyperemia, congestion, thrombosis, embolism infarction, shock, describe virchow"s triad as the pathophysiologic basis of thrombosis, know the difference between reversible and irreversible shock. Hydrostatic pressure toward the arteriolar end of the capillaries forces water out into tissues filtration: opposed by minor hydrostatic pressure of interstitial fluid. Small amount of water that remains in the interstitium is removed by lymphatics and returned to circulation. Fluid movement = k [pc + i) (pi + c: pc = capillary pressure, pi = interstitial pressure, i = interstitial colloid osmotic pressure, c = capillary colloid osmotic pressure. Arterial side: fluid movement is 11 mmhg fluid moves out of the capillary (filtration) Venous side: fluid movement is -4 mmhg fluid moves back into the capillary (reabsorption) There is a net movement of fluid moving out of the capillary. Hypovolemia = deficit of body fluid volume. space.
