PCOL 350 Lecture Notes - Lecture 8: Renal Function, Lactation, Pharmacokinetics
12 Apr 2016
School
Department
Course
Professor
Document Summary
Special populaions: pregnancy & lactaion, pediatrics, geriatrics. Idenify characterisics of drugs that are least likely to cross the fetal-placental barrier and into breast milk: describe the changes in pregnancy that afect the pharmacokineic characterisics (absorpion, distribuion, metabolism, and eliminaion) of drugs, deine teratogen. Idenify and deine each of the pregnancy categories of drugs: outline guidelines to pharmacotherapy during lactaion. Recognize drugs that can decrease breast milk producion: describe the mechanism of acion of domperidone in relaion to its use to increase milk producion, describe the nurse"s role in pharmacological management of pregnant and lactaing women. Blood supply may change to organs responsible for absorpion. Increased levels of progesins: delayed gastric emptying (giving more ime for absorpion) Increased volume of breath and causes pulmonary vasodilaion (higher absorpion of inhaled anestheics only: gastric acidity reduced will afect ionizaion of drug. Increased blood volume can dilute drugs and decrease plasma protein concentraions. Blood low to uterus and kidneys is increased higher distribuion.
