PHSI 208 Lecture Notes - Lecture 19: Acetyl-Coa, Creatine Kinase, Phosphocreatine

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3 Nov 2018
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Muscles need a steady supply of atp to function. Atp needed for: myosin atpase (contraction) atp needed for myosin head to cock forward, ca2+ atpase (relaxation) removing ca2, na+/k+ atpase (after ap in muscle fiber) just like a neuron after an ap. *the first two sources are immediate sources, after the first two, you enter into metabolic processes. Some people have creation supplements so they have more of the phosphocreatine stores. A large amount of glucose is stored in muscle cells in the form of glycogen (glycogenesis) When atp is needed after the first two sources have been used up, glycogen is then converted back to glucose (glycogenolysis) One glucose molecules can then be broken down to pyruvate by glycolysis resulting in the production of two atp molecules. This process occurs in the absence of oxygen and is therefore termed anaerobic metabolism, pyruvate is further broken down to lactate.

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