PHSI 208 Lecture Notes - Lecture 34: Oncotic Pressure, Extracellular Fluid, Mast Cell

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7 Jan 2019
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Blood = a connective tissue composed of cellular elements suspended in an extensive fluid matrix that circulates in the cv system. Blood (5l) is composed of plasma (3l: 92% water, 7% proteins (albumins, globulins and fibrinogen, 1% ions, trace elements and gases. Plasma proteins the primary difference b/w plasma and the interstitial fluid. The ion and organic molecule composition is the same b/w the plasma and the interstitial fluid. Reason: to cause absorption of fluid into the blood vessels (oncotic pressure) Almost all plasma proteins are produced in the liver, some are also produced by lymphoid tissue and wbc"s. Albumins = major plasma proteins (60% of plasma proteins: they are the major contributors to oncotic pressure and they are also carriers of various substances. Globulins = function as clotting factors, enzymes, antibodies, and carriers for various substances. Fibrinogen = forms fibrin threads essential to blood clotting. Blood (5l) is made of plasma (3l) and cellular elements (2l)

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