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Lecture 9

BIOL 130 Lecture 9: Unit 1

3 Pages

Course Code
BIOL 130
Heidi Engelhardt

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Unit 1 intro to the cell By the time an explanation is regarded as a theory it is widely accepted by most scientists in the cell Scientist Contribution Robert Hooke Built 1 microscope The solid ground of science evolution, germ theory, cell theory viewed slices of cork, found little empty rooms cellula Antoni Van worked with glass, improved lens What is more solid than a theory If a theory is thoroughly tested and confirmed over many Leeuwenhoek quality to nearly 300x magnification First to observe single celled years by many tht there is no doubt of its validity it may eventually be regarded as a law. Gravity, laws of organisms animalcules protists, thermodynamics ect. bacteria, blood cells, banded pattern in muscle cells and etc Organelles In 1830, compound microscope improved magnification and Cytosol content of cell excluding organelles resolution, allowed visualization of Cytoplasm all content of cell within plasma membrane excluding nucleus objects less than 1um Lysosomes membrane enclosed organelle containing Beginnings of cell theory digestive enzymes Robert Brown 1883 botanist noticed that every plant Golgi apparatus membrane enclosed in eukaryotic where cell contained a round structure kernel proteins and lipids made in ER are modified and sorted for transportation to other sites (nucleus) Matthias 1838 botanist theorized that all plant Peroxisomes membrane enclosed, use molecular oxygen to Schleiden tissues are composed of cells, and oxidize organic molecules. Contains enzymes tht prod H2O2 and other enzymes tht degrades it embryonic plant always arose from a single cell Cytoskeleton system of protein filaments in cytoplasm of eukaryotic cell tht gives the cell shape and capacity for Theodor 1839 zoologist observed similar Schwann observations in animal cells and is directed movement. Most abundant components are actin, credited for the recognition of structural microfilaments and intermediate filaments similarities bw plants and animals. Also, he formulated the cell theory Electron microscopy SEM scanning electron micrograph scanning surface TEM transmission electron microscope through inside Cell theory All organisms consist of one or more cells Basic properties of cells 1 The cell is the basic unit of structure for all organisms All cells arise only from preexisting cells (added 20 years Use the same genetic program central dogma DNA > RNA > Protein later) Acquire the use energy (bioenergetics) and carry out a Fact and the scientific method variety of chemical reactions (cellular metabolism) A scientific fact attempt to state best understanding based Basic properties of cells 2: Cells on observations and experiments It is valid only until revised or replaced by a better Have may processes tht are highly conserved at the molecular level understanding, based on more careful observations or more discriminating experiments o Membrane structure o Genetic code o ATP synthesizing enzymes What is the scientific method? Make observations o Actin filaments o Eukaryotic flagella Use inductive reasoning to develop tentative explanation Engage in many mechanical activities (hypothesis) Make predictions based on your hypothesis o Transport of materials inout, within o Assembly and disassembly of structures Make further observations or design and carry out controlled o Motility movement experiments to test your hypothesis Respond to environmental signals Interpret your results to see if they support your hypothesis o Move away or toward stimuli What is a theory o Respond to hormones, growth factors, etc Are capable of self regulation homeostasis A hypothesis tht has been tested critically under many diff o Most evident when control systems BD conditions, by many diff investigators using a variety of diff approaches o Defects in DNA replication, DNA repair, cell cycle control
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