BIOL130 Lecture Notes - Lecture 10: Neuroglia, Intermediate Filament, Alpha Helix
15 Dec 2017
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Cytoskeleton: network of fibres forming scaffolding within cytoplasm. Determines cell shape, position of organelles, allows movement of organelles/components within cells (coordinates movement of chromosomes during mitosis) (motility of cell itself) Unlike human skeleton, cytoskeleton is constantly being reorganized (serves as both bones & muscles) Recent advances in microscopy show analogs of major cytoskeleton elements exist in pros Function organization roles in eukaryotic cells, (animal cells grow out of structure near centre of cell (extended periphery) System of tracks for movement of vesicles/organelles (microtubules=rails, motor proteins=engine) turn into mitotic spindle during mitosis! (form cilia/flagella) Microtubule organizing centres: structures where microtubules radiate from centrosomes ( basal body . Motor proteins: powered by hydrolysis of atp (chemical energy mechanical work) base of flagella/cilia) Actin motor: myosin (muscle contraction, vesicle & organelle transport, cell motility cytokinesis. Originally discovered in muscle cells, myosin motors now known to be in all eukaryotic cells. Microtubule motor: kinesins move toward (+) end (large protein superfamily.
