BIOL130 Lecture Notes - Lecture 15: Metaphase, Regulate (Song), S Phase
10 Nov 2015
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Biol 130 lecture 15 unit 9 mitosis, meiosis, cell cycle. Aneuploidy in humans: astonishingly common, accounts for 20% of pregnancy losses, almost always lethal, except for trisomy 21 or trisomy 18, aneuploidy is a human problem, not a mammalian problem. Alternatives to meiosis: asexual reproduction: organism clones itself at an incredibly rapid rate, bacteria, archaebacteria, many protists, many plants, fungi, and some animals. In asexual reproduction, offspring would inherit damaged gene from parent: sexually-reproducing individuals will produce some offspring without the damaged allele, adaptive advantage; damaged alleles eliminated through natural selection. Some cells opt out of the cell cycle. Liver cells are in the g0 phase: do their job instead of spending time and resources dividing: they can re-enter the cell cycle if damage occurs. Control of the cell cycle: mpf: mitosis promoting factor that induces mitosis in mammalian cells, hetero-dimeric protein, cyclin dependent kinase (cdk) is the catalytic subunit; transfers phosphate from.
