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Practise Questions These are questions developed by past students as a study method to aid in understanding course material.

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University of Waterloo
BIOL 239
Christine Dupont

These are practice questions developed to aid in understanding the concepts learned in BIOL 139 Genetics. All questions come from past students, not from the professor or university. As a disclaimer, material may have also changed since this was created. 1. Mendels law of __________________ states that during gamete formation, different pairs of alleles segregate independently of each other. a. product b. sum c. segregation d. independent assortment e. recombination 2. Individuals having two different alleles for a single trait are ____________. a. monohybrids b. dihybrids c. monosomic d. disomic e. polyploid 3. Two individuals with the genotype AaBb are crossed, where dominant alleles for both genes (A and B) are required for pigment production. If they have two offspring, what is the probability the first will have pigment and the second will lack pigment ? a. 0 b. 3/16 c. 9/16 d. 63/256 e. 81/256 4. In a cross between heterozygotes for a particular gene, what ratio in the offspring is associated with recessive lethality ? a. 1:2:1 b. 3:1 c. 2:1 d. 1:1 e. 9:7 5. A method of discovering whether a particular phenotype in two different individuals arises from mutations in the same or separate genes is through a(n) ______________ test. a. heterogeneity b. homogeneity c. complementation d. mutation e. epistasis 6. In karyotypes, homologous pairs of chromosomes are arranged and numbered : a. starting from most strongly staining to least strongly staining b. starting from least strongly staining to most strongly staining c. starting from largest to smallest d. starting from smallest to largest e. randomly 7. The stage of the cell cycle just before mitosis is a. G 0 b. G 1 c. G 2 d. S e. cytokinesis 8. Which of the following does not occur during mitosis: a. sister chromatids attach to spindle fibres from opposite poles b. homologous chromosomes pair along their length c. centromeres are split d. centrosomes move apart towards opposite poles e. all of the above occur during mitosis 9. Duplication of genetic material occurs during a. interphase but not interkinesis b. interkinesis but not interphase c. neither interphase nor interkinesis d. both interphase and interkinesis 10. Which of the following is not observed in plant cells: a. the formation of a cell plate during cytokinesis b. the formation of microtubules c. division of centromeres d. the presence of centrioles or e. the nuclear envelop 11. If a male fruit fly that is hemizygous for a dominant allele specifying an orange colored body is mated with a female fly with recessive wild-type body color, assuming both flies are from true breeding stocks, what phenotypes would be expected in the resultant offspring ? a. all flies would have wild-type bodies b. all flies would have orange bodies c. females would have wild-type bodies and males would have orange bodies d. females would have orange bodies and males would have wild-type bodies e. there would be wild-type and orange bodied flies of both sexes 12. Calculate the chi-square value for the following data set: Phenotypic class Observed Expected AB 43 50 ab 55 50 Ab 48 50 aB 54 50 a. 0.36 b. 0.72 c. 1.09 d. 1.88 e. 1.97 + + + 13. In the cross vg b pr /vg b pr x vg b pr/ vg b pr, where all three genes are linked, and pr is the middle gene, which phenotypic class would be expected to be the smallest in the offspring: a. vg b pr + b. vg + p+ + c. vg b pr d. vg b pr + e. vg b pr 14. If you were to chemically analyze a particular region of a chromosome and determine that 20% of its bases were adenine, then ________ of the bases in this same region would be cytosine. a. 20% b. 25% c. 30% d. 60% e. 80% 15. Which of the following statements concerning mutations is correct: a. forward mutations and reverse mutations occur at roughly the same rate b. forward mutations occur more frequently than reverse mutations c. forward mutations occur less frequently than reverse mutations 16. In deamination, the removal of an amino group converts cytosine to __________. a. adenine b. guanine c. inosine d. thymine e. uracil 17. Flat, planar molecules that can sandwich themselves between successive base pairs and disrupt the machinery for replication are known as: a. base analogs b. oxidators c. thymine dimers d. intercalators e. nucleosomes 18. The experiments of Crick and Brenner, using the mutagen proflavin, helped to establish what important principle: a. the genetic code is degenerate b. the genetic code is almost, but not quite, universal c. introns are regions spliced out of primary transcripts d. resistance arises from random mutation e. a codon is composed of three nucleotides
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