BIOL239 Lecture Notes - Antibody, Cysteine, Herpesviridae
13 Sep 2014
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Thinking back to chromosomal theory of inheritance, there were observations that indirectly place the hereditary materials belonging to the chromosomes by microscopy techniques and tracking chromosomes. And how do you link the genes to this substance: characterization of dna. 1869 identified nuclein" as a weakly acidic, phosphorous-rich material from the nuclei of human white blood cells. Its major component later turned out to be dna (deoxyribonucleic acid) 1923 use of schiff reagent, which stains dna red, shows that it is almost exclusively within the chromosomes. They thought protein was the hereditary material: dna. Its weakly acidic, it gives up hydrogens in solution and it"s got a phosphate backbone on it. But that didn"t prove chromosomes were made up of dna. Dna is the hereditary material or is it protein: characterization of dna. The discovery of dna was a chromosomal constituent did not establish that it had anything to do with genes.
