BIOL303 Lecture Notes - Lecture 3: Ras Subfamily, Oligonucleotide, Blastula

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11 Oct 2017
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Key concepts & study questions for biol 303 (f2017) lecture set 3. Key concepts (you should be able to describe or define these): induction the process by which one cell population influences the development of neighboring cells via interactions at close range. Induction of mesoderm in early gastrula of xenopus(cid:708) (cid:709) Induction of neural tissue in gastrula of xenopus. Induction of eye lens in xenopus neurula stage. Induction between epithelia and mesenchyme can show regional specificity and genetic specificty. example: skin: outer epidermis (epithelial cells from ectoderm, inner dermis (mesenchymal cells from mesoderm) The hedgehog paracrine factor is processed before being secreted (only amino terminal portion of protein is secreted). Also, to be active, hedgehog protein must complexed with a cholesterol molecule and a lipid molecule. A morphogen could be a transcription factor or a paracrine factor (secreted signalling factor) Fgf8 is a paracrine factor belonging to the fibroblast(cid:708) (cid:13558) (cid:709) growth factor family of paracrine factors.

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