BIOL479 Lecture Notes - Lecture 9: Nucleotide Diversity, Coefficient Of Relationship, Metapopulation
Document Summary
A large pop. composed of 2 or more partially isolated demes, such that mating within the metapop. Groups of individuals that mate randomly w/ each other in the absence of inbreeding and assortative mating. The perception of a heterozygote deficit caused by treating two different subpopulations as a single population. Population subdivision reduces heterozygosity (increasing f, the inbreeding coefficient) when we treat more than one population as a single pop. It results non-random mating and hw deviations at the metapopulation level. Formulated to partition the overall reductions in heterozygosity within a metapopulation into its contributing components. Fis : an average measure of f among subpopulations, or the average fractional reduction (or increase) in heterozygosity (hw deviations) within subpopulations. Fst is a measure of the fractional reduction in heterozygosity within the metapopulation as a result of population subdivision alone. Fit is the total departure from hw expectations as a result of. Fit = fis + fst (fis)(fst)