CHEM120L Lecture Notes - Lecture 1: Euchromatin, Sp1 Transcription Factor, Conformational Change
6 Nov 2017
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Molecular bio midterm questions section 8: describe the role of histone acetylation/deacetylation in regulation of transcription. Histones are tightly bound to dna as a result of the positively charged lysine group. Transcription factors regulate histone proteins so that they are either acetylated or deacetylated. This modification regulates transcription by either of the below: Deacetylation represses the gene activity: histone deacetyltransferases found in co-repressor complexes. Activators: co-activator proteins connect transcription factors with general transcription factors to assemble the initiation complex. Tf establish the spatial pattern in an organism (i. e. spinal column in vertebrates) during development. What do they have in common: what is unusual about type 1 and 2 promoters for rnapiii polymerase, describe the mechanism of attenuation of the trp operon. Between splicing of group ii introns and spliceosomal splicing: describe the current model of spliceosomal splicing, list the roles of 5" methyl cap.
