HLTH101 Lecture Notes - Coronary Artery Disease, Peripheral Artery Disease, Coronary Circulation

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Topic 11: cardiovascular and related disorders: introduction, impact. Cardiovascular disorders are the leading cause mortality and morbidity in the 20th century, and again so far in the 21 century: they are responsible for 30% of all deaths globally and roughly the same in. Partial blockage of coronary arteries leads to reduced blood flow to heart muscle if blockage severe, can lead to myocardial infarction (heart attack) Progression: ischemia (low blood flow, leads to anoxia (lack of oxygen in tissue in this case, the heart tissue, leads to infarction (cell death, cerebrovascular disease and stroke* Partial blockage of cerebral arteries if severe, can lead to stroke: peripheral vascular disease* Usually affects legs: heart failure* insult to heart muscle becomes so severe that heart can no longer pump sufficient blood to rest of body, rheumatic heart disease* Heart problems (usually involving the heart valves) caused by previous bacterial infection: pathology. Eventually, they creates a bulge in the arterial lumen.

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