PSYCH261 Lecture Notes - Lecture 17: Retrograde Amnesia, Short-Term Memory, Spatial Memory
Document Summary
Damage to hippocampus interrupt with the most recent learned information. More consolidation less dependent on the hippocampus. Low to moderate cortisol (increase activation of amygdala and hippocampus) Prolonged stress/ release of cortisol (high levels of cortisol damage/kill hippocampus cells memory impairment word-problems, math, etc. ) Entorhinal cortex lesion (lots of errors) Control group (few errors in looking for food in the baited arms) Lesion to hippocampus + related areas (perform poorly affect spatial memory) Place cells record spatial memory regarding to specific locations in the hippocampus. Morris water maze task (cloudy water, animal would need to find the platform that can"t really be seen in the water see the ability to find where the platform is related to external cues) Put rat in variable cues in the pool (learn relatively to the cues to find where the platform is) Damage to hippocampus of rats (learn relatively slower) Non-lesioned rats (learn quickly by trial 2)