BIOL 121 Lecture Notes - Lecture 9: Abiraterone Acetate, Chemotherapy, Colectomy

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24 Jan 2017
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BIOL 121 Full Course Notes
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BIOL 121 Full Course Notes
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Complete dominant heterozygote has same phenotype as homozygous dominant. Incomplete dominance heterozygote has phenotype intermediate between homozygous dominant and homozygous recessive; genotypic ratio phenotypic ratio. Codominance heterozygote has phenotype that is characteristic of both the homozygous dominant and homozygous recessive, not intermediate. Pleiotropy one gene, multiple phenotypic effects. Most common genetic disorder in caucasians of northern european descent. Example of a one gene multiple phenotypic effects . Some symptoms of cystic fibrosis are: secretary glands (e. g. sweat glands) don"t function properly, lungs have build up of heavy mucous, salty skin, digestive problems. Cftr cystic fibrosis transmembrane conductance regulator: protein responsible for chloride transport out of cells, found in membranes that line lungs, liver, pancreas, intestines, reproductive tract and skin. Cftr gene is mutated which then affects the function of mucus and sweat glands. Thick build up of mucus in lungs, pancreas and other organs.

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