CAPS 301 Lecture 1: CAPS 301 - Resting Membrane Potential
21 Sep 2018
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Office hours: monday 1-2pm lsc 1382 (life sci) barry. mason@ubc. ca. Define diffusion, facilitated diffusion, and active transport. Define equilibrium potential and resting membrane potential (rmp) Explain the role of the na+/k+ atpase in the generation and maintenance of a rmp. Describe the effects of changes in extracellular electrolyte levels on cell excitability. Inside of the cell is negative relative to the outside. Diffusion of a solute by random thermal movement. Differential distribution across the membrane of electrically charged ions in solution. Na+/k+ atpase: 3 na+ out, 2 k+ in. Facilitated diffusion: ion channels in the membrane provide a path for na+ and k+, etc. At rest, k+ can leak out of the cell (from leak channels), and the inside gets progressively more (-)ve charged.
