CHEM 203 Lecture Notes - Lecture 33: Tosyl, Sulfonate, Phosphorus Tribromide
Document Summary
Stereochemical complementarity of sulfonate ester vs. pbr3 technology: shorthand for. Possible mode of activation of the -h of a primary or secondary alcohol: Oh connect a potential leaving group l to the oxygen atom. O a generic primary or secondary alcohol a carbonyl compound. Principle: activation of the -h of a primary or secondary alcohol as per the above results in the conversion of the starting alcohol into a carbonyl compound. Principle: the leaving group l in the above reaction is often a metal in a high oxidation state. Chromium (vi) as an especially valuable metal for the above reactions. Oxidation of alcohols to carbonyl compounds with cr(vi) based reagents. Chromiun trioxide, cro3 (inexpensive industrial chemical) as a convenient source of cr(vi) Toxic and carcinogenic properties of cr(vi) compounds including cro3. Conversion of chromiun trioxide into chromic acid, h2cro4 (the cr analog of h2so4) O chromium trioxide: a common source of cr (vi)
