EPSE 312 Lecture Notes - Lecture 6: Centimorgan, Genetic Linkage, Genetic Distance
18 Nov 2018
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How does genetic linkage btwn two genes on the same chromosome change with relative physical position. Translocation move chromosome from one place to another. Independently assort every genes to increase genetic variation. Genetic recombination is nature"s way to independently assort. If they are genetic linked, they are also physically linked. One location recombination increase/decrease the chances of the same pot or neighbouring spot of recombination. At least one crossover btwn each pair of homologous chromosome. Map distance btwn a and b is the biggest. Can calculate distance from a to b by adding distance btwn a and c and c and b. More recombination will put back the parental genes together. Greater genetic distance, less accurate the map distance between. Thus better to add two distance together x: cross over. No recombination then all gametes are parental in genotype. Cross over is guaranteed when distance between genes is larger.
