PHAR 452 Lecture Notes - Lecture 1: Hydromorphone, Liver Disease, Oxycodone

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In a given patient, indicate the severity of pain. Identify reasonable goals of therapy for a given patient experiencing acute pain. Indicate the most common and serious adverse effects and possible drug interactions associated with a given analgesic and indicate what can be done to prevent or manage them. Pain is an unpleasant sensory and emotional experience associated with actual or potential tissue damage, or described in terms of such damage. Pain is a sensation and a perception. Pain is a sensory, cognitive, and emotional phenomenon. Cognitive-evaluative component = thoughts related to cause and significance of pain. Nociceptive pain: involves normal activation of the nociceptive system by noxious stimuli. Neuropathic pain: pain initiated or caused by a primary lesion or dysfunction in the pns or cns. Related to the degree of receptor stimulation by. Often becomes independent of the initial injury processes causing tissue injury.

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