PHAR 454 Lecture Notes - Lecture 11: Insomnia, Paroxetine, Ropinirole
Document Summary
Degeneration of midbrain dopamine neurons, along with other catecholamine neurons and the presence of lewy bodies. Lewy bodies may or may not mean parkinson"s. Tremor (resting: relieved with action, starts unilaterally. Akinesias (lack of movement) and bradykinesia (slowing of movement) Postural instability: feeling of imbalance, tendency to fall. Sialorrhea (drooling) suck on a lozenge so you swallow more. Don"t assume someone with rx for levodopa or dopamine agonist has. Small handwriting, difficulty with fine motor sasks (ex. Bladder urgency, nocturia (anticholinergics: oxybutynin, solifenacin, darifenacin, botulinium toxin) Much overlap between sypmtoms of pd and common symptoms of. Could this be caused by drug therapy? (adverse effect, drug interaction, dose too high or too low) Could this affect this patient/client"s therapeutic plan: in pd avoid . Traditional antipsychotics (prochlorperazine, chlorpromazine, fluphenazine, trifluoperazine, thioridazine, loxapine, haloperidol) Pharmacologic therapy when symptoms interfere with everyday life and ability to carry out daily activities. Before initiating therapy for pd consideration is given to .