PHRM 461 Lecture Notes - Lecture 7: Folic Acid, Prenatal Vitamins, Stretch Marks
Document Summary
Pregnancy wellness: discuss the evidence for use of specific vitamins and minerals for pregnancy wellness. Duration: average of 266 days from conception = 40 weeks from first day of last menstrual period (lmp) Period of organogenesis: 56 days from fertilization (i. e. 1st 10 weeks if counted from lmp or 8 weeks from fertilization) Weigh risks vs. benefits for medication use (motherrisk. org) Limit exposure as much as possible use lowest effective dose, aim for shortest duration possible. Refer to md if otc product fails within specified time period or symptoms progress. Evaluate and manage potential prenatal vitamin + drug interactions. Liver disorder in pregnancy bile acid accumulates in the liver = increased levels in the blood. Previous history (risk in subsequent pregnancy as high as 70%), family history. Potentially serious for baby increased risk of pre-term birth, risk of meconium in amniotic fluid, risk of fetal death. Note potent topical corticosteroids associated with low birth weight.
