BIOL1006 Lecture Notes - Lecture 7: Metaphase, Nucleosome, Interphase
Document Summary
A eukaryote contains a well-defined nucleus, whereas in prokaryotes the chromosome lies in the cytoplasm in an area called the nucleoid. In eukaryotic cells, dna and rna synthesis occur in a separate compartment from protein synthesis. A eukaryote contains a well-defined nucleus, whereas in prokaryotes, the chromosome lies in the cytoplasm in an area called the nucleoid. The size of the genome in one of the most well-studied prokaryotes, e. coli, is 4. 6 million base pairs. The dna is twisted by what is known as supercoiling. Supercoiling means that dna is either under-wound or over-wound from its normal relaxed state. Some proteins are known to be involved in the supercoiling; other proteins and enzymes such as dna gyrase help in maintaining the supercoiled structure. Eukaryotes, whose chromosomes each consist of a linear. Dna molecule, employ a different type of packing strategy to fit their dna inside the nucleus.
