BIOL 1840U Lecture Notes - Bradykinin, Granule Cell, Lamellar Granule
Document Summary
Embryology: surface epithelium derived from endoderm, blood vessels, smooth mm, connective tissue derived from mesoderm, appears as evagination of endoderm during 4th week; developed by 4th month of gestation. Innervation: parasympathetic (vagus) causes sm. mm. of airways to contract, sympathetic causes airway sm. mm. to relax, catecholamines, epinephrine, bronchodilators cause dilation (relaxation) of bronchioloar sm. mm. Blood supply: pulmonary arteries supply deoxygenated blood to lungs for o2, pulmonary veins carry oxygenated blood back to heart, bronchial arteries carry oxygenated blood to nourish lungs, lymphatics found in regions of substantial connective tissue. Pleura: visceral pleura dense connective tissue membrane, provides air-proof barrier; prevents over-inflation, mesothelium simple squamous epithelium coating both pleural surfaces. Lung components: trachea: pseudostratified ciliated columnar epithelium (oriented cilia); goblet and brush cells underlying basement membrane (lamina propria) w/ developed elastic layer extensive smooth muscle layer submucus (& serous) glands secreting glycoprotein, lipid, sufomucin, mixture. Terminal bronchiole: last portion of bronchiole with no alveoli.
