BIOL 1840U Lecture Notes - Corpus Luteum, Estrone, Theca
Document Summary
Adh release & blood volume loss: changes in serum osmolality osmolality => adh secretion; linear relationship+ fear & pain. 3: oxytocin, neurophysin i transport protein carrying oxytocin from hypothalamus to neurohypophysis, circulates as free peptide; life = 2 min, fxn stimulates contraction of uterine mm. & letdown of milk: stimuli parturition, suckling, coitus. Hypothalamic hypophysiotropic hormones: growth hormone releasing hormone (grh, fxn induces production of gh from pituitary; sleep induction, two forms, both are equally active; life = 5 min, binds to a gpcr, part of h-p-growth hormone axis, somatostatin. Inhibit lh & fsh release: stimulate lh release => lh spike, mid-cycle lh surge & fsh surge (key for oocyte expulsion) Prolactin (prl: structure, fsh stimulates spermatogenesis by promoting maturation, polypeptide hormone secreted from lactotropes of anterior pituitary, life = 50 min, several circulating forms but only 1 is active.
