HLSC 2110U Lecture 7: Lecture 7 TCA and Oxidative phosphorylation

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Lecture 7: the citric acid cycle and oxidative phosphorylation. Can take material from the breakdown of some amino acids and can take materials from fatty acids. Glucose when converted to pyruvate, if the cell is bound to proceed into. It produces atp and nadh and fadh electron carriers the respiratory chain into this pathway. Then it will proceed into the electron transport chain. Transported in the mitochondria so it will be in the fluid of the mitochondria and converted into acetyl coa. Pyruvate loses co2 and becomes acetyl coa converted to citrate. Citrate is a 6 carbon atom molecule. Resulting compounds after the conversion of pyruvate acetyl coa. Starts with oxaloacetate and ends up with oxaloacetate. 2 atps however are formed from one glucose due to the 2 pyruvate molecules being used up. If o2 is not present the whole process stops since nadh and fadh need.

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