HLSC 2462U Lecture Notes - Lecture 1: Lipid Peroxidation, Perfusion, Vacuole

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29 Jun 2018
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Altered Physiology I: Lecture 1
Introduction
Course definitions to know. . .
Remission – symptoms may disappear or diminish
Exacerbation – symptoms become worse
Complication – onset of a second condition of someone who is suffering already
Sequelae – unwanted outcomes of a disease or result of trauma (e.g. stroke –
paralysis)
Clinical manifestations – evidence of a disease (signs, symptoms)
Iatrogenic – result of a medical treatment (e.g. Crohn’s steroids causing diabetes in
someone who does not have Crohn’s)
Nosocomial – consequence of being in a hospital (e.g. developing infection)
Signs – observable, objective (blood pressure, temperature)
Symptoms – reported, subjective (e.g. headache, pain)
Diagnosis – naming or identifying of disease or condition
Prognosis – expected outcome of disease or condition
Acute – sudden appearance and generally don’t last long
Chronic – develop slowly and generally for lifetime or long term
What is pathophysiology?
1. What is (normal) physiology?
- how the human body functions
- human physiology
2. What is pathophysiology (or altered physiology)?
- what can go wrong with normal function
3. How relevant is A&P to Altered Phys?
- understanding normal A&P is key for understanding abnormal
ANATOMY = structure
PHYSIOLOGY = function
- anatomy and physiology highly related, dependent
- if something goes wrong with physiology, anatomy affected as well
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Document Summary

Complication onset of a second condition of someone who is suffering already. Sequelae unwanted outcomes of a disease or result of trauma (e. g. stroke paralysis) Clinical manifestations evidence of a disease (signs, symptoms) Iatrogenic result of a medical treatment (e. g. crohn"s steroids causing diabetes in someone who does not have crohn"s) Nosocomial consequence of being in a hospital (e. g. developing infection) Diagnosis naming or identifying of disease or condition. Prognosis expected outcome of disease or condition. Acute sudden appearance and generally don"t last long. Chronic develop slowly and generally for lifetime or long term. What can go wrong with normal function. Understanding normal a&p is key for understanding abnormal. If something goes wrong with physiology, anatomy affected as well. Introduction: types of altered cellular and tissue bio. Decrease in cell size due to a lack of nourishment, can affect an entire organ if enough cells are involved. Physiologic normal part of early development, e. g. thymus.

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