HLSC 2463U Lecture 2: Acute Effects of Atherosclerosis and Hypertension

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11 Jan 2019
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Aneurysm can be a chronic condition but the bursting is an acute complication from going through ischemia and hypoxia of distal tissues. acute hemorrhaging. Thrombus formation break off and travel and become an embolus, blood clot or embolus can actually block even more of the blood vessel internal lumen. Kicks in when there is injury to the endothelial layer of the blood vessel. The platelet plug triggers the clotting cascade and stops rbcs from leaving the. Activation of the coagulation cascade when there is no damage to the vessel wall is called thrombosis (extrinsic pathway: thrombin fibrin blood clot forms. Thrombus remains attached to the bv wall. Thromboembolus blood clot not attached to the bv wall. Thrombophlebitis thrombosis and inflammation in veins. Thombus is a big deal because there is no reason for a blood clot to form. Therefore the plaque blocks the internal diameter of the lumen and leads to hypoxia and ischemia.

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