ANP 1107 Lecture Notes - Lecture 8: Molecular Mimicry, Adrenal Gland, Gangrene

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1107
• Professor: Jackie Carnegie

Document Summary

Regulation of metabolism and body temperature ch 24. Catabolic-anabolic steady states - interactions btwn metabolic pathways body is in constant dynamic flux (molecules constantly being broken down and rebuilt) body can draw on nutrient pools to supply needs; pools linked by key intermediates for interchangeability. Absorptive and post absorptive states events and controls. Catabolism of cellular protein (last resort) only used if fasting is prolonged and during stress (due to secretion of glucocorticoids); process required deamination of aa in liver to generate keto acid followed by their conversion to glucose. Start with skeletal, last to catabolize heart muscles. Glucose sparing mechanisms which use noncarbohydrate fuel molecules for energy (esp. triglycerides) in order to conserve glucose; all tissues and organs (except the brain) switch to using fats as their major energy source. Lipolysis in adipose tissue release free fatty acid to cell which can be oxidized for energy via krebs cycle/oxidative phosphorylation.