ANP 1107 Lecture Notes - Lecture 11: Basal Metabolic Rate, Cool Air, Muscle Atrophy

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1107
• Professor: Jackie Carnegie

Document Summary

Regulation of metabolism and body temperature ch 24. Metabolic rate: (cid:271)od(cid:455)"s rate of e(cid:374)erg(cid:455) e(cid:454)pe(cid:374)diture per hour = total heat produ(cid:272)ed (cid:271)(cid:455) all the (cid:272)he(cid:373)i(cid:272)al rea(cid:272)tio(cid:374)s a(cid:374)d mechanical work of the body. Basal metabolic rate (bmr) rate at which energy is expended (heat produced) by the body per unit time under controlled (basal) conditions; 12 hrs after a meal at rest. Lowest point of metabolism = deepest point in sleeping: bmr is reported as kcal/m2/hr. Stress (physical or emotional) can increase metabolic rate: norepinephrine and epinephrine from adrenal medulla increase metabolic rate primarily by increasing fat catabolism, resulting in heat generation as a by-product. Body temperature and bmr are tightly associated feber assosciated with markedly higher metabolic rates. Most important hormonal factor in regulating bmr is thyroid hormone (metabolic hormone) Extreme emotional states (sympathetic ns) can cause a body temp increase of ~10c, and increased perspiration used to shed heat. Hypothalamus major integrating centre for thermoregulation (principally the preoptic region)