ANP 1105 Lecture Notes - Lecture 4: Polycythemia Vera, Pernicious Anemia, Hemolytic Anemia

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Describe the composition of blood (plasma & formed elements) Describe the structure and function of rbcs; structure and properties of hemoglobin. Describe erythropoiesis, mechanisms of control, and life cycle of erythrocytes. Explain the principal steps and justify the role of platelets and clotting factors in this process. Explain the fibrinolytic system and recognize the action of the major anticoagulants. Differentiate among the various blood types and explain the basis of transfusion reactions. Blood leaves the heart via arteries that branch repeatedly until they become capillary. Oxygen (o2) and nutrients diffuse across capillary walls and enter tissues. Carbon dioxide (co2) and wastes move from tissues into the blood. Oxygen-deficient blood leaves the capillaries and flows in the veins to the heart. This blood flows to the lungs where it releases co2 and picks up o2. The oxygen-rich blood returns to the heart. Blood is the (cid:271)ody"s o(cid:374)ly fluid tissue. It is composed of liquid plasma and formed elements.

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