ANP 1105 Lecture 6: Lymphatic System

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There are two parts of a lymphatic system: lymphatic vessels and lymphatic tissues/organs. Lymphatic vessels: colle(cid:272)t a(cid:374)d retur(cid:374) up to 3 l of (cid:862)leaked(cid:863) fluid plus plas(cid:373)a protei(cid:374)s to the circulatory system. Lymphatic tissues/organs: essential in body defense/resistance to disease. The transport of lymph (once interstitial fluid enters the lymphatic vessels; it is called lymph) beings in microscopic blind-ended lymphatic capillaries. These capillaries are widespread, but they are absent from bones and teeth, bone marrow and the entire central nervous system. Lymphatic capillaries are very permeable due to two unique structural modifications: The endothelial cells forming the walls of lymphatic capillaries are not tightly joined. Instead, the edges of the adjacent cells overlap each other loosely, forming easily opened, flaplike minivalves. Collagen filaments anchor the endothelial cells to the surrounding structures so that any increase in interstitial fluid volume opens the minivalves, rather than causing the lymphatic capillaries to collapse.

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