ANP 1105 Lecture Notes - Lecture 1: Resting Potential, Sodium Channel, Axon Terminal

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Joanne Savory

Document Summary

Axonal transport: through the cooperative effort of motor proteins and cytoskeletal elements (microtubules, and actin laments), substances travel continuously along the axon in both directions, anterograde: moving away from the cell body, retrograde: moving towards the cell body. Substances moved in the anterograde direction: mitochondria, cytoskeletal elements, membrane components used to renew the axon plasma membrane, enzymes needed to synthesize certain neurotransmitters. One basic bidirectional transport mechanism appears to be responsible for axonal transport. It uses different atp dependent motor proteins (kinesin or dynein) depending on the direction. These proteins propel cellular components along the microtubules. Structural classi cation: grouped structurally according to the number of processes extending from their cell body. One is a fused dendrite and the other is an axon. Functional classi cation: groups neutrons according to the direction in which the nerve impulse travels relative to the cns.