ANP 1105 Lecture Notes - Lecture 4: Lipid Bilayer, Extracellular Fluid, Fluid Mosaic Model

• School: University of Ottawa
• Department: Anatomy and Physiology
• Course: ANP 1105
• Professor: Joanne Savory

Document Summary

Plasma membrane: separates 2 of the body"s major uid compartments, the intracellular. The lipid bilayer forms the basic fabric of the membrane. It is constructed largely of phospholipids with smaller amounts of glycolipids and cholesterol. Peripheral proteins: not embedded in the lipid bilayer, attach loosely to integral proteins and are easily removed without disrupting the membrane, some are enzymes, others are motor proteins involved in mechanical function. Ex: changing cell shape during cell division and muscle cell contraction. Cytoskeleton: anchors to plasma membrane, can also interact to receptors, helps cells maintain shape, ex: Cholesterol: overall: reduces general membrane fluidity & stabilizes its structure. Too much cholesterol causes membranes to lose flexibility: 10% of lipid in membrane, stabilize the membrane, keeps fluidity under control. Cell-cell recognition: some glycoproteins (proteins bonded to short chains of sugars which help to make up the glycocalyx) serve as identification tags that are recognized by other cells.