ANP 1105 Lecture 3: Cellular physiology and Nerve pt 1
Document Summary
Dr. joanne savory and dr. m zeroual: cellular physiology of nerve and muscle (ch 3) Fluid mosaic model: double layer of phospholipids with embedded floating proteins. Fluid = moving; mosaic = different particles in the membrane; Phospholipid bilayer constructed of phospholipid and small amounts of glycolipids & cholesterol: hydrophilic head likes water, charged / polar. On the inner and outer (intracellular and extracellular fluids) sides of the membrane: hydrophobic tail fear water, uncharged, nonpolar, made of 2 fatty acid chains. Glycolipid attach to sugar groups; found on the outer membrane surface: about 5% of membrane lipids, sugar group makes the head polar, tails are nonpolar fatty acids. Cholesterol decrease fluidity of membrane and mobility of phospholipids to stabilize its structure: 20% of lipid membrane; has polar and nonpolar region. Transport molecules through the membrane using atp. Enzyme activity integral proteins firmly inserted into lipid bilayer.