ANP 1106 Lecture Notes - Lecture 3: Endochondral Ossification, Costal Cartilage, Hyaline Cartilage

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Topic 3: anatomy of the skeletal system (chapter 6: bones & skeleton tissue) : bony tissues: 1) reacts to amount of applied force=increasing density & roughening bone amount; reduced/eliminated force=decreasing density (ex: paralysis; deposition vs resorption). 2) stores calcium (resorbed/transferred=blood stream when needed). Skeleton: composed=cartilage + fibrous membranes but replaced by bone; remaining found in flexible skeleton tissue regions. Skeletal cartilage: features=dense irregular ct (perichondrium: cartilage compressed=outward expansion resistance; limits cartilage thickness; bv=diffuse nutrients to cartilage cells; form scar tissue=damaged areas=poorly vascularized cartilage repairs badly=aging; cartilage ossification) & 1) no nerve/blood vessels; 2) ground substance (gags chondroitin sulfate/hyaluronic acid/chondronectin (adhesive protein); 3) collagen fibers (sometimes elastic fibers); 4) 80% h20 (resilience) 3 types: hyaline, elastic, fibrocartilage= actively formed=chondroblast (immature cartilage cell); maintained=chondrocyte (mature cartilage cell); lucanae (localized chondrocyte clusters in cartilage) Most abundant; matrix contain fine collagen fibers; chondrocyte=spherical=1-10% volume.

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