BCH 3170 Lecture Notes - Lecture 15: Small Nucleolar Rna, Rna Polymerase Ii, Rna Polymerase Iii

• School: University of Ottawa
• Department: Biochemistry
• Course: BCH 3170
• Professor: Odette Laneuville

Document Summary

Splicing occurs in eukaryotes because you have introns. Splicing is specific to eukaryotes, have to get rid of the introns. Can also generate a bunch of different mrnas from one gene because of alternative splicing. Various types of rna found in eukaryotic cells. Mrna, rrna, trna small nuclear rna, involved in splicing small nucleolar rna maturation of covalent modification. Mirna sirna other types of rna: stuff we still don"t know about. Rna content rrna 80% at equilib. , synthesis capacity, takes aobut 58% of cell. trna. Mrna 3. 5% at equilib. , 33% synthesis capacity. Need a lot of resources for the 3. 5% of mrna. Need to have a ton of rrna and trna, has to be there all the time. Some mrna will be there, but most of the transcript, you need to be able to respond to environmental changes for the cell. That"s why transcription involves so much of the capacity.