BCH 3170 Lecture Notes - Lecture 8: Small Nucleolar Rna, Helix-Turn-Helix, Messenger Rna

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Names for dna strands in rep: 3" to 5" is also called the antisense strand, 5" to 3" is called the sense strand. Convention for reading sequences, must read 5" to 3". If no indication of the ends, you must assume that what is given is written in. 5" to 3" orientation important for replicating and transcribing dna because answer must be provided in the 5" to 3" orientation. Rna polymerase: t replaced by u, sugar lacks a hydroxyl group. Only one kind in prokaryotes, 3 kind in eukaryotes. Type i transcribing gene and something about ribosomal rna. Type ii transcribes messenger rna and small nucleolar rna (most studied) Enzyme is catalyzing the formation of bonds between nucleotides, occurs similarly in eukaryotes and prokaryotes. In eukaryotes, rna pol uses a lot more accessory proteins to more easily access the dna. Made specifically to target prokaryotic rna, of which there is only one type.

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