BIO 1140 Lecture Notes - Lecture 4: Pinocytosis, Glycolipid, Phosphatidylserine

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Model defined in 1972 by singer and. Fluid lipid molecules with embedded, free- floating or anchored proteins o. The lipid portion grants the membrane its fluidity. Two facing sheets/fluid lipid layers - provide structure. Mosaic of different proteins - allow various functions (specificity) o. The mosaic stems from the proteins that span the membrane. The membrane is 2 layers of phospholipids o. Phospholipids are glycerol backbone, a phosphate, some sort of polar functional group. On the backbone there are two fatty acid chains. The membrane is very dynamic, very active: all phospholipids can change their place (lateral diffusion) Within each layer, the lipid continuously change places - for example, lateral diffusion occurs very quickly (approx. Rarely a change from one layer to the other occurs. Fatty acid chains start to flex, then they are all going to cause friction because they are not all the same length/saturated: all of this moves quickly and constantly.

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