BIO 1140 Lecture Notes - Lecture 30: Dna Ligase, Dna Supercoil, Primase
5 Mar 2018
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Mon, march 21-lecture 19 dna replication part 1. Depending on the cell, sometimes all the time or sometimes. They didn"t have any data in terms of the distance between each ring of the dna. Like a winding staircase, going from one step to the next (how much distance between each step). Rosalind franklin"s data (saw it without her knowing), gave them actually measurements, data, and size. All of a sudden the structure was solved. She shot x-ray beams at dna, had a defraction pattern. The 5th carbon outside the ring still counts. The nitrogenous base is bound to the 1st carbon. The hydroxyl group is essential, only place in can bring in an additional nucleotide. Same thing for rna, difference is only one strand. In each eukaryotic cell, must fit all dna into a nucleus. Millions or billions of base pairs (2m long) into a nucleus 6um in diameter. Dna around the histories, 1st level of saving space.
