BIO 1140 Lecture Notes - Lecture 5: Beta Sheet, Protein Structure, Hemoglobin

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Levels of protein structure
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Document Summary

Amino acids have active groups, the amino acids have polarity (look at functional groups/radical groups) backbone is the same for all amino acids. Proteins have a few different areas, their different areas are referred to as domains. Some will be made with alpha helix"s more than beta, and some with more beta than with alpha. Within the membrane you can have a structure that"s predominantly beta pleated sheets; with a few alpha pleated sheets. Important when talking about proteins: sequence structure location and function. There"s a level of folding, folding of beta sheets it onto itself you get a tertiary structure which gives you disulfide bonds. When the sequence gets slightly modified (for example one amino acid) changes the red blood cells to become sickled red blood cells. One amino acid has changed it to form long, inflexible fiberous chains. Because of their shape they"re poor oxygen transporters.

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