BIO 1140 Lecture Notes - Lecture 5: Ethylene Glycol, Hemolysis, Sucrose
Document Summary
Permeability of the red blood cell- hemolysis of sheep blood cells. Table #1: time in seconds needed for red blood cells to reach hemolysis in five different 5 ml solutions. Lipid solubility: the plasma membrane of the red blood cells is composed of a lipid bilayer. The outer and inner sides of the membrane are made up of hydrophilic heads, while between the two layers of the heads are the hydrophobic tails. Therefore, if the solute is non-polar it will be lipid-soluble and diffuse through the membrane. Small polar molecules are additionally able of permeating the the lipid bilayer without aid from a membrane transport protein such as water and urea used in this experiment. Size of solute diffusing: the larger the solute, the longer it takes to diffuse across the cell membrane. This factor was observed in trial 3 with the glycerol as it took longer than the other two trials for hemolysis to occur.