BIO 1140 Lecture Notes - Lecture 4: Motor Protein, Centrosome, Mitosis
12 Aug 2016
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As radical groups get closer, a secondary structure is imposed. Two main secondary structures: alpha helix or beta pleated sheet. Beta sheet appears more rigid, fibre structures - Charged polar proteins alpha helix (more twisty, less rigid) Disulphide bonds contribute to the folding and also solidify the folding (it is not temporary) Can assembly more than one tertiary structures into a quaternary structure; you need 4- Assembling different subunits together = quaternary structure. Proteins can come as a single strand or can be built by combining different portions of tertiary structures. Within a polypeptide, there are areas that form alpha helixes (polar) and other areas that form beta pleated sheets (nonpolar) these areas are called domains. Hemoglobin an example of a protein that needs two alphas and two betas (more than one subunit) Must be correctly folded and assembled to function properly. It is degraded in the lysosomes to use the amino acids for another purpose.
