BIO 1140 Lecture Notes - Lecture 3: Kinesin, Microfilament, Myosin
8 Sep 2016
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Document Summary
Sequences look linear, however there is a shape to it that gives us a secondary structures alpha helix or beta pleated sheet. What determines the shape of one another is the polarity. Non charge polar is more ridged, making a sheets. Hemoglobin needs 2 same sub units (2 alpha 2 beta) and needs to be correctly folded. Sickle celled amenia mutation from the gene causes it to a single amino acid to change in the haemoglobin and causes it to not be folded in the structure. Instead of folded and round we get a long inflexible chain that can create crystal can distort the haemoglobin shape. Can travel effectively however they will clump together with they try to get through something like a junction. Cytoskeleton keeps structure and gives transport, anchors the cells down, cell division. No covalent bonds gives the property of this structure to the cytoskeleton. Basic units of microtubules are tubulin dimers (alpha and beta tubulins)
