BIO 1140 Lecture Notes - Lecture 12: Mitosis, Metaphase, Restriction Point

7 views1 pages

Document Summary

Prevents cells to go forwards when its not ready. Mpf = maturation promoting factor = cyclin + cdk complex. G1/s cyclins (e): bind their cdk(2) near end of g1 and lead cell into dna replication. S-cyclin (a): bind cdk (20 during s phase and are required for dna replication. M- cyclins (a,b) cdk(1) to promote the event of mitosis. G1-cyclins (d): (in most cells) bind cdk (4,6) to promote passage through restriction point in late1. Quiescence cells are differentiated by cell cycle is arrested in g0 this can be permanent or temporary. Dna damaged; g0 and cell repair activated dna repaired; resume g1/s or quiescence. P53 various proteins cdk2 s phase or cdk 1 m phase. Dna is still uncondensed but duplicated, intacted nuclar envalop spindles will develop and pull away create daughter chromatids. Checkpoint is at the end of m phase end of metaphase.

Get access

Grade+20% OFF
$8 USD/m$10 USD/m
Billed $96 USD annually
Grade+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
40 Verified Answers
Class+
$8 USD/m
Billed $96 USD annually
Class+
Homework Help
Study Guides
Textbook Solutions
Class Notes
Textbook Notes
Booster Class
30 Verified Answers

Related Documents