BIO 3102 Lecture Notes - Lecture 8: 18S Ribosomal Rna, Neanderthal Genome Project, Mitochondrial Eve
29 Aug 2016
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Document Summary
Applications of molecular phylogenetics: archaeology/paleontology ( ancient dna analysis, conservation biology, forensic science, taxonomy. Power & pitfalls of pcr (polymerase chain reaction: rapid amplification of specific genomic regions using very small amounts of dna, but damaged dna may lead to sequence artifacts, or ancient dna may be contaminated with modern dna. Otzi"s last meals: dna analysis of the intestinal content . Intergenic regions in ribosome rna gene clusters evolve rapidly: bacterial population, h. pylori bacteria in the stomach that cause ulcers, oldest specimen ever sequenced, geographically distinct bacterial strains to reconstruct human migrations. Contamination of modern dna: article published in nature: but in fact this turned out to be contaminating. The future of ancient dna: technical advances and conceptual shifts : cumulative number of ancient genomes published. Information about dispersal of modern human populations from ancient dna: out-of-africa mitochondrial eve hypothesis, follow eve: mitochondrial dna maternally inherited, y chromosome data in agreement.
