BIO 3303 Lecture Notes - Lecture 19: Sensillum, Signal Transduction, Tas1R1
20 Mar 2018
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Nerves go through the bone and into interneurons that go to the brain. Allow lipophillic odorants to dissolve in aqueous mucus layer. Very small chemical changes in structure changes what you smell. Eg octanol (rose) octanoic acid (sweaty) one oxygen added. Cribriform plate is at the back --> likely not to break if you break your nose. Compare and contrast taste and smell exam i think, emphasis. G protein cascade --> sodium and calcium channels open --> depolarization --> cl out more na out --> signal fire. Nobel prize for figuring out that or multigene family that is g coupled receptors. Eg the green goes to a green glomerulus, red etc. Know the ratio of blue to green to red etc. Combination to figure out what the smell is. Each colour more sensitive to certain types so some will fire more some less.
