BCH 4123 Lecture Notes - Lecture 11: Tachypnea, Tachycardia, Cardiomyopathy
13 Feb 2017
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Midterm: name and student number on every page. Any condition brought on by sudden, reduced blood flow to the heart: associated with signs or symptoms of a heart attack. Development: may start at young age, fatty streak (small lesion in arteries) caused by a number of things that damage epithelial cells. Low grade inflammatory response within vessel: synthesis of extracellular matrix, foam cells recruited due to oxidized ldl, cell migration and proliferation, years and years of low grade inflammatory response. Exacerbated by poor diet, low exercise, hypertension etc: thin fibrous cap can weaken and burst. Lysing contents into blood stream and thrombus forms downstream. Unstable angina: small thrombus occludes blood flow temporarily. Higher risk for mi or cardiac arrestj: thick fibrous plaque will not burst. Stable angina: as heart demands more blood flow, the plaque will prevent full perfusion and cause chest pain. Ecg: good at detecting medium to large mi.
