BCH 4123 Lecture Notes - Lecture 21: Otitis Media, Osteoarthritis, Cough Medicine
Document Summary
Systematic reviews and guidelines in pathology and laboratory medicine. In most cases, antibiotics are not needed, but there are some cases that they are absolutely essential: can"t identify who needed it and who doesn"t. No surgery had a better outcome than a placebo surgery. Multiple different types of drug combinations did not relieve symptoms more than placebo. Narrative review: written by expert in the field, used to address complex diagnostic problems, do no follow explicit methods and criteria and may have bias towards one"s one publications and ideas. Systematic review: overview of multiple primary studies which locate, synthesize, and appraise the evidence in a systematic way, answer a specific question, follow a pre-defined protocol, often the first step in producing clinical practice guidelines, personnel. Clinicians, researchers, methodologists, statisticians, writers, literature screeners, librarians. Identify the problem and scope of review: ask a key question of the review based on previously identified need.