BIO 1140 Lecture Notes - Neurofilament, Lamin, Globular Protein
Document Summary
The cytoskeleton lecture notes: grows, shrinks and changed shape rapidly and constantly (dynamic nature, all of the cytoskeletal elements are working together in a cell, functions of the cytoskeleton, functions include: The provision of structure and support (1) Intracellular transport (2) allows eukaryotic cells to achieve greater sizes than prokaryotic cells. The positioning of organelles within the cell (4) can move and position organelles. The generation of force for cell movement relies on cytoskeleton during embryonic development. Contributing to cell division microfilaments involved in cytokinesis and movement of chromosomes. Mechanical strength in animal cells e. g. keratin ifs. Link to desmosomes and hemidesmosomes: epidermolysis bullosa simplex, only nuclear lamins in other eukaryotes, desmosomes, microfilaments, structure. Flexible, helical fibres of ~7 nm diameter. At one end of the actin filament (+ end) there will be an actin monomer with atp bound to it and at the other end of the filament (end that"s away from the atp bonding site.
