BIO 2133 Lecture Notes - Dna Polymerase, Phosphodiester Bond, Helicase
21 Aug 2013
School
Department
Course
Professor
Document Summary
Describe the molecular anatomy of genes and genomes. Watson and crick created a model of dna that featured two strands of intertwining nucleotides that allowed for separation and reformation of the dna within the cell allowed for the replication of genetic material. A primer (3"oh) group is added onto the forming strand. Dna polymerase can organize the bond on the. 5" end, but ligase makes bonds on the 3": single-stranded binding proteins bind to the dna while it"s single-stranded to keep it from being degraded. Dna polymerase can only act from 5" to 3". Discuss the hallmark features and organization of chromosomes. Describe the hallmark features and organization of genes and explain the role of each of these features. Alec jeffreys, exonerated an innocent man as well as linked both murders. How do you know there"s a gene question asked in class (flowchart) (forward and reverse. Scientific evidence question asked, hypothesis, evidence that might support or reject the hypothesis.
